C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) A61K 39/395 (2006.01) C07H 1/08 (2006.01) C12N 5/10 (2006.01) C12P 21/00 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2321113
The present invention relates to anti-IPG antibodies, and in particular monoclonal antibodies produced by hybridoma cell lines 2F7, 2D1 and 5H6, and the use of these and other similar antibodies in the treatment and diagnosis of pre-eclampsia or diabetes, especially type I diabetes. A method of producing anti-IPG antibodies by immunising an animal with IPG unconjugated to an immunogenic carrier is also disclosed.
La présente invention concerne des anticorps anti-IPG, et plus particulièrement des anticorps monoclonaux produits par les lignées cellulaires hybridomes 2F7, 2D1, et 5H6. L'invention concerne également l'utilisation des anticorps susmentionnés et d'autres anticorps similaires, afin de diagnostiquer et de traiter la prééclampsie ou les diabètes, en particulier les diabètes du type I. L'invention concerne enfin une méthode de production desdits anticorps anti-IPG, par immunisation d'un animal avec un IPG non conjugué à un excipient immunogène.
Mato Jose
Nieto Isabel Varela
Prieto Jesus
Rademacher Thomas William
Williams Phillip
Bereskin & Parr
Rademacher Group Limited
Rodaris Pharmaceuticals Limited
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