Anti-invasion factor containing cultures

C - Chemistry – Metallurgy – 12 – N

Patent

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195/46, 195/86

C12N 5/00 (2006.01) A61K 35/32 (2006.01) A61L 27/38 (2006.01) C12N 5/06 (2006.01) C12P 21/00 (2006.01)

Patent

CA 1154697

ABSTRACT Chondrocytes are cultrued to prodcue cartilage tissue from which an anti-invasion factor (AIF) may be recovered. Mammalian cartilage providing at least about 60% viable chodrocytes is enzymatically digested to denude the cells of their extracellular matrix. The denuded cells are plated at high density and cultured to produce cartilage tissue.

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