A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2154278
The medicament comprises as active ingredient at least a monoclonal antibody directed against the humain molecule LFA-1 in isotonic aqueous solution for perfusion and at least one stabilizing agent such as tris(hydroxymethyl)aminomethane and the Tween 380. For a solution of 1 litre, the medicament may comprise from 0.1 to 10 g, particularly approximately 1 g of monoclonal antibody, and from 0.1 to 10 g, particularly 2.4 g of tris(hydroxyméthyl)aminomethane or analogue and from 0.1 to 10, and particularly 2 per 10 thousand Tween 380.
Le médicament comprend à titre de principe actif au moins un anticorps monoclonal dirigé contre la molécule LFA-1 humaine en solution aqueuse isotonique pour perfusion et au moins un agent de stabilisation tel que le tris (hydroxyméthyle) aminométhane et le Tween ?80. Pour une solution d'un litre, médicament peut comprendre de 0,1 à 10 g, notamment 1 g environ d'anticorps monoclonal, et de 0,1 à 10 g, notamment 2,4 g de tris (hydroxyméthyle) aminométhane ou analogue et de 0,1 à 10, et notamment 2 pour dix mille de Tween ?80.
Alberici Gilles
Caudrelier Pierre
Hourmant Maryvonne
Le Mauff Brigitte
Soulillou Jean-Paul
Imtix-Sangstat
Robic
LandOfFree
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