Anti-lps enriched immunoglobulin preparation for use in...

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/40 (2006.01) A61K 35/20 (2006.01) A61K 39/395 (2006.01) A61P 31/00 (2006.01) A61P 37/04 (2006.01) C07K 16/02 (2006.01) C07K 16/04 (2006.01) C07K 16/44 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2760096

The invention relates to the use of preparations enriched with anti LPS antibodies, such as those derived from mammalian colostrum or avian eggs, and optionally further antibodies against disease-associated antigens, colostrums, milk or milk product component/s and any adjuvants for treating, delaying or preventing the progression of a pathologic disorder such as chronic liver disease, cirrhosis and any complication or disorder associated therewith. The invention further relates to combined compositions comprising a combination of anti-LPS enriched antibody preparations and antibodies recognizing at least one antigen specific for a pathologic disorder and uses thereof in the treatment of immune-related disorders.

L'invention concerne l'utilisation de préparations enrichies en anticorps anti-LPS tels que ceux dérivés du colostrum mammaire ou d'oeufs aviaires, et éventuellement d'autres anticorps contre des antigènes associés à des maladies, des colostrums, du lait ou un/des composant(s) de produits laitiers et de tout autre adjuvant pour traiter, retarder ou prévenir la progression d'un trouble pathologique tel qu'une hépatite chronique, une cirrhose ou toute complication ou trouble associés à celles-ci. L'invention porte également sur des compositions combinées comportant une combinaison de préparations d'anticorps enrichies en anti-LPS et d'anticorps reconnaissant au moins un antigène spécifique d'un trouble pathologique, ainsi que sur des utilisations de ces compositions pour le traitement de troubles immunitaires.

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