Anti-lymphotoxin antibodies

Details Anti-lymphotoxin antibodies Anti-lymphotoxin antibodies

C - Chemistry, Metallurgy

07

K

C07K 16/24 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2748757

The instant invention is based, at least in part on the identification of a new class of antibodies that result, e.g., in improved LT blocking capabilities. Methods of making the subject binding molecules and methods of using the binding molecules of the invention to antagonize LT.beta.R signaling are also provided.

La présente invention est basée, au moins en partie, sur l'identification d'une nouvelle classe d'anticorps qui conduisent, par exemple, à des capacités améliorées de blocage des LT. L'invention porte également sur des procédés de production des molécules de liaison en objet et sur des procédés d'utilisation des molécules de liaison de l'invention pour antagoniser la signalisation LTßR.

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