C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/24 (2006.01) B01D 15/36 (2006.01) B01D 15/38 (2006.01) C07K 1/18 (2006.01)
Patent
CA 2600601
The present invention provides for compositions of anti-M-CSF antibodies that are substantially free of endotoxin. Also provided are methods of treating M- CSF-mediated disorders with pharmaceutical formulations of anti-M-CSF antibodies having reduced endotoxin levels, including inflammatory diseases and neoplasia disorders.
L'invention concerne des compositions d'anticorps anti-M-CSF sensiblement exemptes d'endotoxine. L'invention concerne également des méthodes permettant de traiter des troubles induits par M-CSF à l'aide de formulations pharmaceutiques d'anticorps anti-M-CSF présentant un niveau d'endotoxine réduit, notamment, les maladies inflammatoires et des troubles néoplasiques.
Devalaraja Madhav Narasimha
Fedechko Ronald William
Pharmacia & Upjohn Company Llc
Sim & Mcburney
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