Anti-melanoma antibody mg-21 for diagnosis and therapy of...

Details Anti-melanoma antibody mg-21 for diagnosis and therapy of... Anti-melanoma antibody mg-21 for diagnosis and therapy of...

C - Chemistry, Metallurgy

12

P

195/1.109

C12P 21/08 (2006.01) C07K 16/30 (2006.01) C12N 5/06 (2006.01)

Patent

CA 1309040

ABSTRACT An antibody MG-21 which is directed against a tumor- associated glycolipid antigen and which is capable of activating serum complement or antibody dependent cellular cytotoxicity is described. This antibody finds use in the therapy of cancers particularly melanoma and glioma. Proper administration of the antibody results in lysis of the tumor cells in vivo.

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