Anti-microbial proteins

Details Anti-microbial proteins Anti-microbial proteins

C - Chemistry, Metallurgy

12

N

C12N 15/29 (2006.01) A01H 5/00 (2006.01) A01N 37/18 (2006.01) A01N 43/50 (2006.01) A01N 65/00 (2006.01) A61K 38/16 (2006.01) C07H 21/04 (2006.01) C07K 1/16 (2006.01) C07K 14/415 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/24 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2116201

Abstract Anti-microbial proteins isolated from sugar beet, wherein the anti-microbial proteins exclude chitinases and glucanases. Said proteins include a pure protein selected from those depicted in SEQ ID Nos 2, 5 and 8, or a functionally equivalent analogue thereof in which one or more amino acids have been added, substituted or removed withoutsubstantially reducing the protein's anti-microbial activity, or mixtures of such proteins or analogues. A synergistic anti-fungal effect is observed if at least one of the AX proteins is combined with a WIN protein. The invention also provides recombinant DNA comprising a sequence encoding a protein according to the invention, a vector comprising said DNA and transformed plants comprising said DNA. The invention further provides an anti-microbial composition containing one or more of the said proteins, and a process for combatting fungi or bacteria which comprises exposing them to said proteins or compositions. 36

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