C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/02 (2006.01) A61K 38/44 (2006.01) A61K 47/48 (2006.01) C12N 9/96 (2006.01) C12N 11/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2155043
The present invention relates to an novel anti- motoneuron-disease agent, comprising superoxide dismutase conjugated with lecithin through chemical crosslinking represented in the following generic formula (PC-SOD) as an effective ingredient: SOD-[C(O)-(CH2)n-C(O)-X]m , wherein SOD represents superoxide dismutase and X represents a residue of lysolecithin having a hydroxy group at position 2 of glycerol whose hydrogen atom of the hydroxyl group at position 2 is removed. A pharmaceutical agent of the present invention may improve symptoms of motoneuron diseases such as amyotrophic lateral sclerosis etc. by oral or parenteral administration. The present invention also relates to a novel treatment method for motoneuron disease by administrating PC-SOD and novel use of PC-SOD as a medical composition for preparing an agent for treating motoneuron disease.
Ikeda Ken
Iwasaki Yasuo
Kinoshita Masao
Kobayashi Tomoko
Shiojima Toshiya
Dennison Associates
Sam Research Corporation
LandOfFree
Anti-motoneuron-disease agent does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Anti-motoneuron-disease agent, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-motoneuron-disease agent will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1889600