C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) G01N 33/574 (2006.01) C12N 15/09 (2006.01)
Patent
CA 2691734
An antibody that binds to Mucin17 (Muc17) is disclosed. The antibody of the present invention preferably binds to the peptide of SEQ ID NO:3 and does not bind to the peptide of SEQ ID NO:4 or the peptide of SEQ ID NO:5. Also disclosed are an anti-cancer agent, preferably an anti-cancer agent for pancreatic cancer, which comprises the antibody of the present invention, as well as a method of diagnosing cancer using the antibody of the present invention, preferably the antibody of the present invention that does not bind to the secreted-form of Muc17.
L'invention concerne un anticorps capable de se lier à la mucine 17(Muc17). De préférence l'anticorps peut se lier à un peptide présenté dans SEQ ID NO:3, mais ne peut se lier à des peptides présentés dans SEQ ID NO:4 et SEQ ID NO:5. Elle concerne également un agent anticancéreux, de préférence un agent anticancéreux contre le cancer du pancréas, qui comprend l'anticorps. Elle concerne en outre un procédé pour le diagnostic du cancer, qui se caractérise par l'utilisation de l'anticorps qui ne peut se lier à Muc17 sécrété.
Forerunner Pharma Research Co. Ltd.
Smart & Biggar
LandOfFree
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