C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/22 (2006.01) A61K 39/395 (2006.01) A61P 3/00 (2006.01) A61P 21/00 (2006.01)
Patent
CA 2624935
Anti-myostatin antibodies are identified that are characterized as having high affinity and may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing bone density, or for the treatment of various disorders in mammalian and avian species.
L'invention concerne des anticorps anti-myostatine caractérisés par une haute affinité et pouvant être des anticorps chimériques, humanisés ou entièrement humains, des immunoconjugués de ces anticorps ou des fragments de ceux-ci se liant à l'antigène. Les anticorps selon l'invention sont utiles pour augmenter la masse musculaire, augmenter la densité osseuse ou pour traiter divers troubles chez des espèces mammifères et aviaires.
Davies Julian
Jones Bryan Edward
Korytko Andrew Ihor
Mitchell Pamela Jean
O'bryan Linda O. (nee Tobias)
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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