Anti-neoplastic compositions and uses thereof

Details Anti-neoplastic compositions and uses thereof Anti-neoplastic compositions and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61P 35/00 (2006.01) C07K 14/075 (2006.01) C07K 14/47 (2006.01) C12N 15/62 (2006.01) C12N 15/861 (2006.01) C12N 15/867 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2362995

Disclosed is a nucleic acid composition consisting essentially of a first nucleic acid sequence encoding a chimeric CDKi protein and a second nucleic acid sequence encoding an adenovirus E4 protein, wherein the first and second nucleic acid sequences are operably linked to at least one regulatory sequence.

L'invention concerne une composition d'acide nucléique consistant essentiellement en une première séquence d'acide nucléique codant une protéine CDKi chimère et une deuxième séquence d'acide nucléique codant une protéine E4 d'adénovirus, les première et deuxième séquences d'acide nucléique étant fonctionnellement liées à au moins une séquence régulatrice.

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