Anti-nik antibodies and uses thereof

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/40 (2006.01) A61K 39/395 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2540521

An antibody or antibody preparation being capable of specifically binding the amino acid sequence of NF-&kgr;B-inducing kinase (NIK) MAP3K14, or a specific portion thereof, and of thereby regulating a biochemical activity of NIK, and/or enabling detection of NIK or a specific portion thereof.

L'invention concerne un anticorps ou une préparation d'anticorps capable de se lier spécifiquement à la séquence d'acides aminés de la kinase à induction NF-?B (NIK)/MAP3K14 ou à une partie spécifique correspondante et, donc, de réguler une activité biochimique de NIK et/ou de permettre la détection de NIK ou d'une partie spécifique associée.

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