C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
167/139, 167/37,
C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 16/24 (2006.01) C12N 5/12 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2039231
ON-0066A ABSTRACT The present invention relates to monoclonal antibodies that define Oncostatin M. The monoclonal antibodies of the invention are capable of binding to Oncostatin M, inhibiting Oncostatin M receptor binding, and/or inhibiting Oncostatin M bioactivity. Such antibodies may be used to detect the presence of Oncostatin M and/or to modulate Oncostatin M bioactivities in an in vivo or in vitro system.
Linsley Peter S.
Radka Susan F.
Shoyab Mohammed
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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