Anti-oncostatin m monoclonal antibodies

C - Chemistry – Metallurgy – 12 – P

Patent

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167/139, 167/37,

C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 16/24 (2006.01) C12N 5/12 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2039231

ON-0066A ABSTRACT The present invention relates to monoclonal antibodies that define Oncostatin M. The monoclonal antibodies of the invention are capable of binding to Oncostatin M, inhibiting Oncostatin M receptor binding, and/or inhibiting Oncostatin M bioactivity. Such antibodies may be used to detect the presence of Oncostatin M and/or to modulate Oncostatin M bioactivities in an in vivo or in vitro system.

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