C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/46 (2006.01)
Patent
CA 2580140
This invention relates to anti-OX40L antibodies and, in particular, to anti- OX40L antibodies and variants thereof that contain a Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from inflammatory diseases.
La présente invention concerne des anticorps anti-OX40L, et plus particulièrement des anticorps anti-OX40L et certaines de leurs variantes qui contiennent une partie Fc dérivée d'une origine humaine et qui ne se lient pas au facteur complémentaire C1q. Ces anticorps présentent des propriétés nouvelles ressortant de l'invention, et qui sont source de bienfaits pour un patient souffrant de maladies inflammatoires.
Endl Josef
Eugui Elsie
Fuentes Maria
Graus Yvo
Labrijn Aran
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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