C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) A61K 31/704 (2006.01) A61N 5/10 (2006.01)
Patent
CA 2680945
The invention also provides antibodies that bind to human PDGFR&agr; and neutralize activation of the receptor. The invention further provides a methods for neutralizing activation of PDGFR&agr; and methods of treating a mammal with a neoplastic disease using the antibodie alone or in combination with other agents.
Fatatis Alessandro
Huber Jim
Loizos Nick
Ludwig Dale L.
Plymate Stephen R.
Drexel University College Of Medicine
Gowling Lafleur Henderson Llp
Imclone Llc
Imclone Systems Incorporated
University Of Washington
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