C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/20 (2006.01) C07K 14/445 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2362477
Compositions that inhibit the binding of Plasmodium falciparum to erythrocytes are provided. More particularly, antibodies specific for Plasmodium falciparum binding proteins and blocking peptides that prevent the binding of Plasmodium falciparum are included in the present invention. The methods provided utilize the antibody and peptide compositions provided herein and include methods for the diagnosis, prevention, and treatment of Plasmodium falciparum diseases such as malaria as well as methods for the detection of Plasmodium falciparum in biological samples and culture media.
L'invention concerne des compositions qui inhibent la liaison de Plasmodium falciparum aux érythrocytes. L'invention concerne plus particulièrement des anticorps spécifiques aux protéines de liaison de Plasmodium falciparum et aux peptides de blocage qui empêchent la liaison de Plasmodium falciparum. Les procédés de l'invention se basent sur les compositions d'anticorps et de peptides et comprennent des procédés de diagnostic, de prévention et de traitement de maladies liées à Plasmodium falciparum telles que le paludisme ainsi que des procédés de détection de Plasmodium falciparum dans des échantillons biologiques et des milieux de culture.
Narum David L.
Sim Kim Lee
Entremed Inc.
Finlayson & Singlehurst
The Government Of The United States Of America
LandOfFree
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