Anti-retroviral agents, compositions, methods and uses

Details Anti-retroviral agents, compositions, methods and uses Anti-retroviral agents, compositions, methods and uses

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 39/21 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2548181

HIV gp41 mimetibody polypeptides and encoding polynucleotides are disclosed. Methods of utilizing the polypeptides to reduce or inhibit HIV fusion with a cell membrane and entry into target cells are also disclosed.

La présente invention concerne des polypeptides à corps mimétique gp41 du VIH et des polynucléotiques codants. Les méthodes décrites dans cette invention consistent à utiliser les polypeptides pour réduire ou inhiber la fusion du VIH avec une membrane cellulaire et la pénétration dans des cellules cibles.

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