Anti-rhinovirus agents

Details Anti-rhinovirus agents Anti-rhinovirus agents

C - Chemistry, Metallurgy

07

C

260/627.1, 260/4

C07C 43/20 (2006.01) C07C 29/62 (2006.01) C07C 43/23 (2006.01) C07C 69/40 (2006.01) C07C 301/00 (2006.01) C07C 309/66 (2006.01) C07C 321/26 (2006.01) C07C 323/12 (2006.01)

Patent

CA 1181760

ABSTRACT OF THE DISCLOSURE Compounds having antirhinovirus activity, and effective in a method for prophylaxis and treatment of a rhinovirus infection, have the formula Image wherein A is a bond or CH2; Y is a bond, O or S; X is O or S; Z and Z' are each H, C1-4 alkyl, C1-4 alkoxy, OH or halogen; and n is an integer from 4 to 12; or an ester thereof with a solubiliting pharmaceutically acceptable acid or a salt of said ester. Pharmaceutical compositions containing the above compounds are also part of the invention, as are processes for their preparation and their use for the prevention of and treatment of rhinovirus infections therewith.

369912

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