Anti-sense oligonucleotides against hsv-1, and their...

Details Anti-sense oligonucleotides against hsv-1, and their... Anti-sense oligonucleotides against hsv-1, and their...

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) A61K 31/70 (2006.01) A61K 31/7088 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2132265

The invention relates to novel antisense oligonucleotides having the sequences AO1 (Herp099): 5'-G C G G G G C T C C A T G G G G G T C G-3' AO2 (Herp018): 5'-G C A G G A G G A T G C T G A C O A G G-3' AO3 (Herp002): 5'-G G G G C G G G G C T C C A T G G G G G-3' AO4 (Herp112): 5'-G G C G G G G C T C C A T G G G G G T C-3' AO5 (Herp034): 5'-G G G G C T C C A T G G G G G T C G T A-3' AO6 (Herp024): 5'-A A G A G G T C C A T T G G G T G G G G-3' or AO7 (Herp028): 5'-G G C C C T G C T G T T C C G T G G C G-3' and their mixtures, homologs or modified forms, against HSV 1.

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