Anti-sickling beta-globin protein, compositions and methods...

Details Anti-sickling beta-globin protein, compositions and methods... Anti-sickling beta-globin protein, compositions and methods...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 35/18 (2006.01) A61K 48/00 (2006.01) C07K 14/805 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2199832

Gene therapy methods and compositions for high level expression of anti- sickling beta-globin proteins in erythroid cells for treating Sickle Cell Disease are described.

On décrit des procédés du domaine de la thérapie génique et des compositions permettant une expression élevée de bêta-globines actives contre la drépanocytose dans les cellules érythrocytaires, pour traiter cette maladie.

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