Anti-siglec-15 antibody

Details Anti-siglec-15 antibody Anti-siglec-15 antibody

C - Chemistry, Metallurgy

12

N

C12N 15/09 (2006.01) A61K 39/395 (2006.01) A61P 1/02 (2006.01) A61P 3/14 (2006.01) A61P 19/08 (2006.01) A61P 19/10 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) C07K 16/18 (2006.01) C07K 16/46 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2750836

Provided is a pharmaceutical composition for treating and/or preventing abnormal bone metabolism targeting a protein encoded by a gene strongly expressed in osteoclasts. Specifically provided is a pharmaceutical composition containing an antibody which specifically recognizes human Siglec-15 and has an activity of inhibiting osteoclast formation, and the like.

L'invention concerne une composition pharmaceutique destinée à traiter et/ou à prévenir des anomalies du métabolisme osseux, et qui cible une protéine codée par un gène pouvant être exprimé fortement dans des ostéoclastes. L'invention concerne spécifiquement, entre autres, une composition pharmaceutique contenant un anticorps capable de reconnaître spécifiquement une protéine Siglec-15 humaine et qui possède une activité d'inhibition de la formation d'ostéoclastes.

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