Anti-tumor compounds

Details Anti-tumor compounds Anti-tumor compounds

C - Chemistry, Metallurgy

07

D

C07D 487/00 (2006.01)

Patent

CA 2593049

Compounds of formula (I); wherein A, D, Q, T, U, V, W, X, Y, Z, R1, and formula (II) are as defined herein. This invention also relates to a method of inhibiting tubulin polymerization, or treating cancer or an angiogenesis- related disorder with one of these compounds.

L'invention porte sur des composés de formule (I) dans laquelle A, D, Q, T, U, V, W, X, Y, Z, R1, et de formule (II) qui sont tels que définis dans la demande. Cette invention porte également sur une méthode d'inhibition de la polymérisation de la tubuline ou du traitement du cancer ou d'une maladie liée à l'angiogenèse avec l'un de ces composés.

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