Anti-tumor comprising boroproline compounds

Details Anti-tumor comprising boroproline compounds Anti-tumor comprising boroproline compounds

A - Human Necessities

61

K

A61K 38/55 (2006.01) A61K 31/69 (2006.01) A61K 38/05 (2006.01) A61K 38/20 (2006.01) A61K 38/21 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2373643

A method for treating subjects with abnormal cell proliferation is provided. The method involves administering to subjects in need of such treatment an effective amount of an agent of Formula (I), to inhibit cell proliferation such as that associated with tumor growth and metastasis. A method for inhibiting angiogenesis in an abnormal proliferative cell mass by the administration of an agent of Formula (I) is also provided. The preferred compounds are boroproline derivatives.

L'invention concerne une méthode de traitement de patients sujets à une prolifération cellulaire anormale. Cette méthode consiste à administrer aux patients nécessitant un tel traitement, une quantité efficace d'un agent de formule (I), pour inhiber la prolifération cellulaire telle celle liée à une croissance tumorale ou à une métastase. Ladite invention a également trait à une méthode d'inhibition d'une angiogenèse dans une masse cellulaire proliférant anormalement, en administrant un agent de formule (I). Les composés préférés sont des dérivés de boroproline.

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