Anti-tumor platinum complexes, their preparation and their...

Details Anti-tumor platinum complexes, their preparation and their... Anti-tumor platinum complexes, their preparation and their...

C - Chemistry, Metallurgy

07

F

167/119, 260/292

C07F 15/00 (2006.01) A61K 31/555 (2006.01)

Patent

CA 1308723

ABSTRACT Compounds of formula (I): Image (I) in which: A and B are separately monoamines or together diamines; and Z is a group of formula (II) or (III): Image (II) (III) (in which R1, R2 and R7 are various organic groups, n is 0, 1 or 2 and X is a direct carbon-carbon bond or lower alkylene) show valuable anti-tumor activity and may be prepared by reacting an amine-platinum complex with a compound providing the group represented by Z.

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