Anti-tumor synergetic composition

Details Anti-tumor synergetic composition Anti-tumor synergetic composition

A - Human Necessities

61

K

A61K 31/396 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2361828

There are provided the combined use of 4-demethoxy-3'-deamino-3'-aziridinyl-4'- methansulfonyl daunorubicin or 4-demethoxy-N,N-bis(2-chloroethyl)-4'- methansulfonyl daunorubicin and an anti-neoplastic anti-mitotic compound and/or a platinum derivative in the treatment of tumors, as well as in the prevention or treatment of metastasis or in the treatment of tumors by inhibition of angiogenesis.

Cette invention concerne l'utilisation conjointe de 4-déméthoxy-3'-désamino-3'-aziridinyl-4'-méthanesulfonyle daunorubicine ou de 4-déméthoxy-N,N-bis(2-chloroéthyl)-4'-méthanesulfonyle daunorubicine et d'un composé antimitotique anti-néoplastique et/ou d'un dérivé du platine, pour le traitement des tumeurs, ainsi que pour la prévention ou le traitement des métastases ou pour le traitement des tumeurs par inhibition de l'angiogénèse.

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