Anti-vegf antibody

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/22 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) C07K 16/00 (2006.01) C07K 16/46 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2719400

An antibody is provided. In certain cases, the antibody comprises: a) a heavy chain variable domain that comprises CDR regions that are substantially identical to the heavy chain CDR regions of a selected antibody and b) a light chain variable domain that comprises CDR regions that are substantially identical to the light chain CDR regions of the selected antibody, where the antibody binds a selected target.

La présente invention concerne un anticorps. Dans certains cas, l'anticorps comprend: a) un domaine variable à chaîne lourde qui comprend des régions de détermination de complémentarité ou CDR (Complementary Determination Region) qui sont sensiblement identiques aux régions CDR des chaînes lourdes d'un anticorps sélectionné, et b) un domaine variable à chaîne légère qui comprend des régions CDR qui sont sensiblement identiques aux régions CDR à chaînes légères de l'anticorps sélectionné, lequel anticorps se lie à une cible sélectionnée.

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