Anti-vibrio anguillarum vaccine (gava-3) for the prevention...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 1/20 (2006.01) A61K 39/106 (2006.01) C07K 14/28 (2006.01) C12N 1/36 (2006.01)

Patent

CA 2294618

The invention relates to an anti-Vibrio anguillarum vaccine (GAVA-3) for the prevention of vibriosis in the turbot and Salmonidae fish and the process for producing such vaccine. The vaccine is comprised of three bacterial strains of Vibrio angillarum isolated from a turbot: strain CECT 5031 (serotype 01), strain CECT 5032 (serotype 02, sub-group 02.alpha.) and CECT 5033 (serotype 02, sub-group 02.beta.), and is also comprised of their extracellular products. Both the strains and the extracellular products are inactivated with formol. The vaccine applies to the field of aquaculture.

L'invention concerne un vaccin anti-Vibrio anguillarum (GAVA-3) pour la prévention de la vibriose chez les turbots et les Salmonidés et son procédé d'obtention. Le vaccin est composé de trois souches bactériennes de Vibrio anguillarum isolées à partir d'un turbot : une souche CECT 5031 (sérotype 01), une souche CECT 5032 (sérotype 02, sous-groupe 02.alpha.) et une souche CECT 5033 (sérotype 02, sous-groupe 02.beta.) et de leurs produits extracellulaires. Les souches et les produits extracellulaires sont inactivés en présence de formol. Le vaccin trouve une application dans le domaine de l'aquaculture.

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