Anti-viral 7-deaza l-nucleosides

Details Anti-viral 7-deaza l-nucleosides Anti-viral 7-deaza l-nucleosides

C - Chemistry, Metallurgy

07

H

C07H 19/16 (2006.01) A61K 31/7076 (2006.01) A61P 31/12 (2006.01) C07H 19/044 (2006.01)

Patent

CA 2470521

The present invention comprises 7-deaza L-nucleosides having unexpectedly high inhibitory activity against the hepatitis B virus. The invention further comprises pharmaceutical compositions comprising such compounds as well as methods of treating mammals, paarticularly humans, infected with HBV and other viral infections.

L'invention concerne des 7-déaza L-nucléosides possédant une activité inhibitrice élevée inattendue contre le virus de l'hépatite B. Elle concerne aussi des compositions pharmaceutiques comprenant de tels composés ainsi que des méthodes de traitement de mammifères, en particulier des humains, infectés par le virus de l'hépatite B et d'autres virus.

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