Anti-viral sulfur-analogues of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 211/54 (2006.01) A61K 31/435 (2006.01) C07D 491/04 (2006.01) C07D 491/056 (2006.01)

Patent

CA 2140930

Novel derivatives of 1-deoxynojirimycin are disclosed which have thio or sulfinyl substituents at C-2 or C-3. They can be represented by formulae (1,11). These compounds are useful inhibitors of lentiviruses such as visna virus and human immunode- ficiency virus. Methods of chemical synthesis of these derivatives and intermediates therefor are also disclosed.

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