Antiallergic marine biopolymers

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/731 (2006.01) A61P 11/06 (2006.01) A61P 27/14 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2726221

The present invention relates to pharmaceutical compositions based on carrageenan as an active ingredient, for use as a medicament in the prophylactic or therapeutic treatment of allergic conditions or diseases, with the proviso that the car-rageenan comprises iota- and/or kappa-carrageenan and is substantially free of lambda carrageenan. Typically, the invention re-lates to liquid formulations, gels and dry powder compositions comprising iota- and/or kappa-carrageenan and, optionally, one or more non-carrageenan therapeutic agents for administration to the respiratory tract, the gastrointestinal tract or the eyes. The com-positions of the invention have been found to be efficacious in the prevention and treatment of type I allergies and additionally, may exert an adjuvant function upon combined mucosal administration with non- carrageenan therapeutic agents.

La présente invention porte sur des compositions pharmaceutiques à base de carraghénine en tant qu'ingrédient actif, pour une utilisation en tant que médicament dans le traitement prophylactique ou thérapeutique de conditions allergiques ou de maladies allergiques, à la condition que la carraghénine comprenne un carraghénine iota et/ou kappa et soit sensiblement exempte de carraghénine lambda. Typiquement, l'invention porte sur des formulations liquides, des gels et des compositions en poudre sèches renfermant de la carraghénine iota et/ou kappa et, éventuellement, un ou plusieurs agents thérapeutiquement non-carraghénine pour une administration au tractus respiratoire, au tractus gastro-intestinal ou aux yeux. Les compositions de l'invention se sont avérées être efficaces dans la prévention et le traitement d'allergies de type I et, de plus, peuvent exercer une fonction adjuvante lors dune administration mucosale combinée avec des agents thérapeutiques non-carraghénine.

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