Antianaphylactic and antibronchospastic n-...

Details Antianaphylactic and antibronchospastic n-... Antianaphylactic and antibronchospastic n-...

C - Chemistry, Metallurgy

07

D

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C07D 295/15 (2006.01) C07D 339/06 (2006.01) C07D 401/12 (2006.01) C07D 413/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1269980

ANTIANAPHYLACTIC AND ANTIBRONCHOSPASTIC N-BENZHYDRYLDIAZACYCLOALKYLALKANANILIDES ABSTRACT New piperazine derivatives of general formula: Image are described, wherein R is hydrogen or lower alkyl, A is straight of branched lower alkyl, and R1 and R2 are respectively hydrogen, amino, alkylamino, dialkylamino mono or di(hyroxyalkyl) amino, imidazolyl, morpholino, piperidino, N-alkylpiperazino, 1,3-dithiolan-2-ylidinamio, N-alkylureido, but R1, and R2 are not both hydrogen, isomers mixture thereof, individual enantiomers and pharmaceutically acceptable acid addition salts thereof. The new compounds exhibit a high antianaphylactic and antibronchospastic activity.

510539

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