C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 1/00 (2006.01) A61K 31/56 (2006.01) C07J 11/00 (2006.01)
Patent
CA 2558014
Compositions and methods for treating mammalian diseases or conditions characterized by undesirable angiogenesis by administering an effective amount of a compound of the formula I (I), or formula II (II), wherein Ra is selected from -OCH3, OCH2CH3 or -CCCH3; and Z is selected from >C(H)-OH, >C(H)-O-alkyl, >C(H)-O-sulfamate, where alkyl is a linear, branched and/or cyclic hydrocarbon chain comprising 1 to 10 carbons.
Cette invention concerne des compositions et de méthodes permettant de traiter chez des mammifères des pathologies ou des états caractérisés par une angiogenèse indésirable, ceci par administration d'une dose efficace d'un composé représenté par la formule: (I) ou (II). Dans cette formule, Ra est pris dans -OCH3, OCH2CH3 ou -CCCH3; et Z est pris dans >C(H)-OH, >C(H)-O-alkyle, >C(H)-O-sulfamate, dans lequel alkyle est une chaîne hydrocarbonée linéaire, ramifiée et/ou cyclique comprenant de 1 à 10 atomes de carbone.
Agoston Gregory E.
Lavallee Theresa M.
Shah Jamshed H.
Suwandi Lita
Treston Anthony
Entremed Inc.
Finlayson & Singlehurst
LandOfFree
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