Antiangiogenic drug to treat cancer, arthritis and retinopathy

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 237/42 (2006.01) A61K 31/195 (2006.01) C07C 237/22 (2006.01) C07C 311/46 (2006.01)

Patent

CA 2332535

Compounds having Formula (I) or pharmaceutically acceptable salts or prodrugs thereof, are useful for treating pathological states which arise from or are exacerbated by angiogenesis. The invention also relates to pharmaceutical compositions comprising these compounds and to methods of inhibiting angiogenesis in a mammal.

L'invention concerne des composés de formule (I), des sels ou des promédicaments de ceux-ci, acceptables au plan pharmaceutique, utiles pour le traitement d'états pathologiques résultant de l'angiogenèse ou exacerbés par cette dernière. L'invention porte aussi sur des compositions pharmaceutiques comprenant lesdits composés et sur des méthodes d'inhibition de l'angiogenèse chez un mammifère.

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