A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/00 (2006.01) A61K 38/02 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) C07K 5/00 (2006.01) C07K 7/00 (2006.01) C07K 7/08 (2006.01) C07K 7/22 (2006.01) C07K 14/575 (2006.01) C07K 14/655 (2006.01)
Patent
CA 2362574
The invention relates to the use of peptides individually or in combination, for treating and/or preventing angiogenesis. It also relates to the use of peptide analogs or a combination of peptides referred to as MuJ-7 as anticancer drugs in restricting the tumor growth and spread by inhibiting tumor angiogenesis. MuJ-7, in addition inhibits metastasis through its antiangiogenic activity in all cancers. The invention also relates to a pharmaceutical composition containing either individual peptides or in combination, and methods of treatment of human beings and animals for curing and/or preventing angiogenesis.
La présente invention concerne l'utilisation de peptides, pris individuellement ou en association, de façon à traiter et/ou prévenir l'angiogenèse. L'invention concerne également l'utilisation d'analogues de peptides ou d'une association de peptides désignée comme MuJ-7 en tant qu'anticancéreux pour restreindre la croissance et l'extension tumorale et par blocage de l'angiogenèse tumorale. Le MuJ-7 bloque en outre la métastase de par son activité anti-angiogenique dans le cas de tous les cancers. L'invention concerne aussi, d'une part une composition pharmaceutique contenant des peptides pris un à un ou en association, et d'autre part des procédés destinés au traitement de l'homme ou d'autres animaux nécessitant un traitement curatif ou préventif de l'angiogenèse.
Burman Anand C.
Jaggi Manu
Mathur Archana
Mukherjee Rama
Prasad Sudhanand
Dabur Research Foundation
Marks & Clerk
National Institute Of Immunology
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