Antiangiogenic peptides, polynucleotides encoding same and...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/57 (2006.01) A61K 35/12 (2006.01) A61K 38/48 (2006.01) A61K 47/48 (2006.01) C07K 7/06 (2006.01) C12N 9/68 (2006.01) C12N 9/96 (2006.01) C12N 15/62 (2006.01) C12P 21/06 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2253243

Mammalian kringle (5) fragments of plasminogen and kringle (5) fusion proteins are disclosed as compounds for treating angiogenic diseases. Methods and compositions for inhibiting angiogenic diseases are also disclosed.

L'invention a trait à des fragments de kringle (5) ainsi qu'à des protéines hybrides de kringle (5) en tant que composés permettant de traiter des maladies angiogéniques. Elle concerne également des procédés ainsi que les compositions afférentes permettant d'inhiber le développement de maladies angiogéniques.

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