Antiarrhythmic 2-phenethylpiperidine compounds and preparation

Details Antiarrhythmic 2-phenethylpiperidine compounds and preparation Antiarrhythmic 2-phenethylpiperidine compounds and preparation

C - Chemistry, Metallurgy

07

D

260/291.1, 260/2

C07D 211/34 (2006.01) C07D 211/26 (2006.01)

Patent

CA 1192199

Abstract of the Disclosure 2-Phenethylpiperidines bearing urea, thiourea, and amidin substituents in the ortho-position of the phenethyl moiety have been synthesized and demonstrate useful antiarrhythic properties. These novel compounds are prepared by reaction of appropriately substituted o-amino-phenethylpiperidines with appropriately substituted phenyl isoshiocyanstes, phenyl isocyanates, or phenyl imino esters.

406583

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