Antiarrhythmic agents

Details Antiarrhythmic agents Antiarrhythmic agents

C - Chemistry, Metallurgy

07

D

167/207, 260/308

C07D 215/38 (2006.01) A61K 31/33 (2006.01) C07D 263/56 (2006.01) C07D 307/81 (2006.01) C07D 307/82 (2006.01) C07D 333/58 (2006.01) C07D 333/66 (2006.01)

Patent

CA 1298840

Abstract Title: "Antiarrhythmic Agents" Compounds of the formula:- Image ----- (A) and their salts, where R is -NHSO2(C1-C4 alkyl), -NH2 or -NO2; R1 is C1-C4 alkyl; and "Het" is a group of the formula:- Image where R2 is H, CH3 or C2H5; R3 is -NHSO2(C1-C4 alkyl), -NH2 or -NO2; and X is 0, S or NR4 where R4 is H or CH3; with the proviso that when one of R and R3 is -NO2, then the other is not -NH2. The compounds of the formula (A) in which both R and R3 are -NHSO2(C1-C4 alkyl) are antiarrhythmic agents. The reamining compounds of the formula (A) are synthetic intermediates. PLC 441

567187

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