Antibacterial 3',5-disubstituted 2,4'-dihydroxybiphenyl...

A - Human Necessities – 61 – K

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Details

A61K 8/34 (2006.01) A61K 31/05 (2006.01) A61P 1/02 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 2601904

The invention provides an antiplaque oral composition containing an orally acceptable carrier and an antibacterial effective amount of compound (I). In the structure, R1 and R2 are independently a hydrogen atom or a lower C1-4 alkyl group and R3 and R4 are independently an alkenyl or alkyl group having from 1 to 20 carbon atoms, with the proviso that R3 and R4 are not both 2- propenyl or n-propyl when R1 and R2 are both hydrogen atoms. Also included are oral compositions containing the compound (I).

L'invention porte sur une composition orale antiplaquettaire contenant un excipient acceptable pour être administré par voie orale et une quantité efficace antibactérienne du composé (I). Dans la structure, R1 et R2 représentent, indépendamment, un atome d'hydrogène ou un groupe C1-4 alkyle inférieur, et R3 et R4 représentent, indépendamment, un groupe alcényle ou alkyle possédant de 1 à 20 atomes de carbone, à condition que R3 et R4 ne représentent pas tous les deux 2-propényle ou n-propyle, lorsque R1 et R2 représentent des atomes d'hydrogène. L'invention porte également sur des compositions orales contenant le composé (I).

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