Antibacterial aminoglycoside analogs

Details Antibacterial aminoglycoside analogs Antibacterial aminoglycoside analogs

C - Chemistry, Metallurgy

07

H

C07H 15/222 (2006.01) A61K 31/7036 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2706369

Compounds of structure (I): having antibacterial activity are disclosed, including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R8 and R9 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

L'invention concerne des composés de structure (I) qui présentent une activité antibactérienne, notamment des stéréo-isomères, des sels et des pro-médicaments pharmaceutiquement acceptables de ceux-ci, Q1, Q2, Q3, R8 et R9 étant tels que définis ici. Elle concerne également des procédés associés à la préparation et à l'utilisation de ces composés, ainsi que des compositions pharmaceutiques comprenant ces composés.

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