Antibacterial and antitumor agents ll-e33288e-i and...

C - Chemistry – Metallurgy – 12 – P

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C12P 1/06 (2006.01) A61K 35/74 (2006.01) C07G 11/00 (2006.01) C07H 17/00 (2006.01) C12P 19/60 (2006.01) C12P 19/64 (2006.01)

Patent

CA 1337760

Antibacterial and antitumor agents designated LL-E33288.epsilon.-I and LL-E33288.epsilon.-Br, their production by strains of Micromonospora echinospora ssp. calichensis designated NRRL-15839, NRRL-15975 and NRRL-18149, and chemical processes for their production, are disclosed. Novel intermediates prepared in the chemical processes are disclosed. Processes for producing reductively aromatized derivatives of other antibiotics are also disclosed.

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