Antibacterial aqueous ophthalmic formulations containing...

A - Human Necessities – 61 – K

Patent

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A61K 31/5383 (2006.01) A61K 9/00 (2006.01) A61K 47/36 (2006.01) A61P 27/02 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2346631

The aqueous ophthalmic formulation for the treatment and prevention of infections contains ofloxacin as active ingredient and a chitosan having a weight average molecular weight of 500,000 - 5,000,000 Daltons and a deacetylation degree of 30 - 90 % as solubilizing agent of ofloxacin. Chitosan having a deacetylation degree of 30 - 90 % may be also used for solubilizing ofloxacin suspended in an aqueous media having a substantially neutral pH in any other applications.

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