Antibacterial carbapenems, compositions and methods of...

Details Antibacterial carbapenems, compositions and methods of... Antibacterial carbapenems, compositions and methods of...

A - Human Necessities

61

K

A61K 31/40 (2006.01) C07D 477/14 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2306399

Compounds of formula (I), as well as pharmaceutically acceptable salts thereof are disclosed. R2 is H and R3 is C1-3 alkyl, or R2 and R3 taken in combination represent C1-3 alkylidene. Pharmaceutical compositions and methods of treatment are also included. The compounds are useful against methicillin resistant staphylococci (MRSA).

L'invention concerne des composés correspondant à la formule (I), ainsi que des sels de ceux-ci, acceptables sur le plan pharmacologique. Dans cette formule R?2¿ représente H et R?3¿ représente alkyle C¿1-3?, ou bien R?2¿ et R?3¿ combinés ensemble représentent alkylidène C¿1-3?. L'invention concerne également des compositions pharmaceutiques ainsi que des méthodes de traitement. Ces composés sont utiles contre les staphylocoques résistants à la méthicilline.

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