Antibacterial composition containing primicin

C - Chemistry – Metallurgy – 07 – H

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C07H 15/00 (2006.01) A61K 9/06 (2006.01) A61K 31/155 (2006.01) A61K 31/40 (2006.01) A61K 31/70 (2006.01)

Patent

CA 1288345

ABSTRACT This invention relates to a primicin-containing colloidal basic gel comprising 5-30 % of primicin and 95 70 % of M- -methyl-pyrrolidone-2. The invention also relates to antibacterial compositions particularly for the treatment of acne vulgaris comprising as active ingredient 0.1-100 % of a primicin-containing collo- idal basic gel, if desired together with further antimicrobial active ingredients, in admixture with 99.9-0 % of usual inert pharmaceutical filling, diluting and other formulating addi- tives. The invention also relates to combination composition comprising as active ingredient 1-60 % of a primicin-containing colloidal basic gel and 0.1-40 % of further pharmaceutical active ingredient(s), e g. one or more antibiotic(s), chemo- therapeutical agent(s), fungistatic or fungicidal agent(s), steroidal or non-steroidal antiinflammatory agent(s), epi- thelogenic agent(s), local anaesthetic(s), and/or vitamin(s).

524501

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