Antibacterial composition for oral administration

Details Antibacterial composition for oral administration Antibacterial composition for oral administration

A - Human Necessities

61

K

167/188

A61K 31/545 (2006.01) A61K 9/20 (2006.01) A61K 31/715 (2006.01) A61K 47/40 (2006.01) C08B 37/00 (2006.01)

Patent

CA 1334934

An antibacterial composition for oral administration comprising pivaloyloxymethyl-(6R,7R)-7[(Z)- 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamide]-3-[(Z)-2- (4-methylthiazol-5-yl)-ethenyl]cephem-4-carboxylate, .beta.- cyclodextrin and a pharmaceutically acceptable carrier is disclosed. The addition of .beta.-cyclodextrin remarkably improves the dispersibility of the substance ME1207 to thereby promote the absorption of the same. Thus, the absorbability of the substance ME1207 administered at a hungry state is elevated to a level comparable to that achieved by administering the same after meals.

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