Antibacterial compositions comprising metal phthalocyanine...

A - Human Necessities – 61 – K

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A61K 31/4035 (2006.01) A61K 31/195 (2006.01) A61K 31/315 (2006.01) A61K 31/695 (2006.01) A61P 31/02 (2006.01) C07D 487/22 (2006.01) C09B 47/04 (2006.01) C09B 47/08 (2006.01)

Patent

CA 2484070

The present invention relates to pharmaceutical compositions comprising metal phthalocyanine analogues of formula (I) and metal chelating compounds having a good bioavailability and enhanced photoinactivation properties against Gram negative bacteria; and to their use for in vivolex vivo applications, such as blood and blood derivatives sterilization.

La présente invention concerne des compositions pharmaceutiques contenant des analogues de phtalocyanine de métaux de formule (I), et des composés de chélation de métaux ayant une bonne biodisponibilité et des propriétés améliorées de photoinactivation contre des bactéries Gram négatif. L'invention concerne également l'utilisation de ces compositions dans des applications <i>in vivolex vivo</i> telles que la stérilisation du sang et de dérivés sanguins.

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