Antibacterial condensed carbapenemes

C - Chemistry – Metallurgy – 07 – D

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C07D 477/00 (2006.01) A61K 31/40 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2105388

2105388 9215587 PCTABS00016 Compounds of formula (I) in which R1 represents a hydrogen atom or a hydroxyl protecting group; R2 represents a hydrogen atom, a carboxyl protecting group or a cation derived from an inorganic base or an organic base; R3 represents the group O(CH2)nR4 in which n is an integer from 2 to 6 and R4 represents a halogen atom or a hydroxy, C1-3alkoxy, C1-3alkylthio, azido, cyano, nitro or quaternary ammonium group N+R5R6R7X- wherein R5 and R6 independently represent a C1-3alkyl group, R7 is a C1-2 alkyl group and X- is a pharmaceutically acceptable anion and metabolically labile esters, salts and solvates thereof, and processes for their production.

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