Antibacterial fluoroquinolone analogs

Details Antibacterial fluoroquinolone analogs Antibacterial fluoroquinolone analogs

C - Chemistry, Metallurgy

07

D

C07D 471/14 (2006.01) A61K 31/554 (2006.01) A61P 31/04 (2006.01) C07D 498/14 (2006.01) C07D 513/14 (2006.01)

Patent

CA 2712586

Compounds having antibacterial activity are disclosed. The compunds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein A, B, D, E, G, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Linvention concerne des composés présentant une activité antibactérienne. Les composés présentent la structure (I) suivante : incluant leurs stéréo-isomères, leurs sels pharmaceutiquement acceptables et leurs promédicaments, où A, B, D, E, G, R1, R2, R3, R4, R5, R6 et R7 sont tels que définis ici. Linvention concerne également des procédés associés à la préparation de tels composés, ainsi que des compositions pharmaceutiques contenant de tels composés.

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