Antibacterial phage peptides and methods of use thereof

Details Antibacterial phage peptides and methods of use thereof Antibacterial phage peptides and methods of use thereof

C - Chemistry, Metallurgy

12

N

C12N 9/50 (2006.01)

Patent

CA 2739717

The present invention is directed to isolated and chimeric polypeptides of bacteriophage origin having antibiotic activity and use thereof in the treatment and control of bacterial infections. Specifically, the present invention is directed to the use of a novel antibacterial polypeptide derived from bacteriophage F87s/06 and chimeric constructs thereof, and their use for the treatment and control of infections caused by gram-positive bacteria, including Staphylococcus aureus.

La présente invention concerne des polypeptides isolés et chimères provenant de bactériophage ayant une activité antibiotique et lutilisation de ceux-ci dans le traitement et le contrôle dinfections bactériennes. Spécifiquement, la présente invention concerne lutilisation dun nouveau polypeptide antibactérien dérivé du bactériophage F87s/06 et des constructions chimères de celui-ci, et leur utilisation pour le traitement et le contrôle dinfections causées par des bactéries Gram positif, comprenant Staphylococcus aureus.

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