Antibiotic a 40926 complex and its pure factors pa, pb, a,...

C - Chemistry – Metallurgy – 07 – G

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195/89, 530/15.0

C07G 11/00 (2006.01) C07K 9/00 (2006.01) C12P 1/06 (2006.01)

Patent

CA 1317900

8217-150 Abstract of the Disclosure The present invention concerns a new antibiotic substance arbitrarily denominated antibiotic A 40926 complex and its factors antibiotic A 40926 factor A, antibiotic A 40926 factor B, antibiotic A 40926 factor B0 anti- biotic A 40926 factor PA and antibiotic A 40926 factor PB, a process for pro- ducing them by culturing the new strain Actinomadura sp. ATCC 39727 or an A 40926 producing variant or mutant thereof and the use of these new anti- biotic substances in the treatment of infectious diseases involving microorganisms susceptible to them. The antibiotic substances of the invention are glycopeptidic substances belonging to the vancomycin class of antibiotics which have binding capacity to Acyl-D-Alanyl-D-Alanine. LP 629 `

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